and EOS are two important elements in the whole process of allergic inflammation. B cells to produce specific IgE binding to the receptor on the surface of mast cells and basophils, when the same allergen original re-entering the body, combined with the surface of mast cells IgE activates mast cells to degranulation, release of inflammatory neurotransmitters (histamine, bradykinin, and leukotrienes) and cytokines, the role of the blood vessels and nerves of the Timberland Homme nasal mucosa to produce clinical symptoms, Timberland Homme these neurotransmitters and cytokines acting on the EOS, the nasal epithelial and submucosal EOS infiltration increased activation and release of ECP, MBP and other neurotransmitters. Pathophysiology pathological changes telangiectasia, increased permeability and glandular secretion, and eosinophil. These pathological changes remission to return to normal, repeated attacks can cause proliferative changes in Nike Jordan the mucosal epithelium, leading to mucosal hypertrophy and polypoid changes. Such as infection, can Air Max Femme 2013 be